{"id":34181,"date":"2021-10-08T00:26:46","date_gmt":"2021-10-08T00:26:46","guid":{"rendered":"https:\/\/\/%e7%99%bb%e9%9d%a9%e7%86%b1%e7%97%85%e6%af%92%e6%94%b9%e8%ae%8a%e4%ba%86%e7%b5%90%e6%a7%8b%ef%bc%8c%e9%81%bf%e5%85%8d%e4%ba%86%e5%ae%bf%e4%b8%bb%e7%9a%84%e5%85%8d%e7%96%ab%e5%8f%8d%e6%87%89%ef%bc%8c\/"},"modified":"2021-10-08T00:26:46","modified_gmt":"2021-10-08T00:26:46","slug":"%e7%99%bb%e9%9d%a9%e7%86%b1%e7%97%85%e6%af%92%e6%94%b9%e8%ae%8a%e4%ba%86%e7%b5%90%e6%a7%8b%ef%bc%8c%e9%81%bf%e5%85%8d%e4%ba%86%e5%ae%bf%e4%b8%bb%e7%9a%84%e5%85%8d%e7%96%ab%e5%8f%8d%e6%87%89%ef%bc%8c","status":"publish","type":"post","link":"https:\/\/\/%e7%99%bb%e9%9d%a9%e7%86%b1%e7%97%85%e6%af%92%e6%94%b9%e8%ae%8a%e4%ba%86%e7%b5%90%e6%a7%8b%ef%bc%8c%e9%81%bf%e5%85%8d%e4%ba%86%e5%ae%bf%e4%b8%bb%e7%9a%84%e5%85%8d%e7%96%ab%e5%8f%8d%e6%87%89%ef%bc%8c\/","title":{"rendered":"\u767b\u9769\u71b1\u75c5\u6bd2\u6539\u8b8a\u4e86\u7d50\u69cb\uff0c\u907f\u514d\u4e86\u5bbf\u4e3b\u7684\u514d\u75ab\u53cd\u61c9\uff0c\u75ab\u82d7\u548c\u6cbb\u7642\u85e5\u7269"},"content":{"rendered":"
\n

\u622a\u81f3\uff082020\uff09\u3002\u5e746\u670813\u65e5\u7684\u4e00\u5468\u4e2d\uff0c\u65b0\u52a0\u5761\u5171\u67091158\u4f8b\u767b\u9769\u71b1\u75c5\u4f8b\uff0c\u662f2014\u5e74\u4ee5\u4f86\u6bcf\u9031\u8a18\u9304\u7684\u6700\u9ad8\u767b\u9769\u71b1\u75c5\u4f8b\u3002\u76ee\u524d\u5728\u65b0\u52a0\u5761\u6d41\u884c\u7684\u767b\u9769\u71b1\u75c5\u6bd2\u8840\u6e05\u578b3\uff08DENV3\uff09\u53ef\u80fd\u6703\u767c\u751f\u5287\u70c8\u7684\u7d50\u69cb\u8b8a\u5316\uff0c\u5f9e\u800c\u4f7f\u5176\u80fd\u5920\u62b5\u6297\u75ab\u82d7\u548c\u6cbb\u7642\u85e5\u7269\uff0c\u63ed\u793a\u675c\u514b\u570b\u5927\u91ab\u5b78\u9662\u79d1\u5b78\u5bb6\u7684\u4e00\u9805\u7814\u7a76\u7d50\u679c\u3002\u7814\u7a76\u7d50\u679c\u767c\u8868\u65bc \u81ea\u7136\u901a\u8a0a\u3002<\/i>\u53ef\u4ee5\u6307\u5c0e\u6297\u767b\u9769\u71b1\u611f\u67d3\u7684\u6709\u6548\u75ab\u82d7\u548c\u6cbb\u7642\u5291\u7684\u958b\u767c\u3002<\/p>\n

\u767b\u9769\u71b1\u611f\u67d3\u65b0\u5a1b\u6a02\u57ce\u9ad4\u9a57\u91d1<\/a>\u5373\u4f7f\u516c\u5171\u885b\u751f\u90e8\u9580\u5728\u8207\u4e4b\u9b25\u722d\u5a1b\u6a02\u57ce\u9ad4\u9a57\u91d1500<\/a>o\u542b\u6709\u51a0\u72c0\u75c5\u6bd2\u7684\u50b3\u64ad\u3002\u767b\u9769\u71b1\u75c5\u6bd2\u8840\u6e05\u578b2\uff08DENV2\uff09\u4ee5\u524d\u662f539\u73a9\u6cd5\u4e8c\u5408<\/a>\u4e3b\u8981\u7684\u8840\u6e05\u578b\uff0c\u4f46\u5728\u5c07\u8fd1\u4e09\u5341\u5e74\u5f8c\uff0cDENV3\u5728\u65b0\u52a0\u5761\u91cd\u65b0\u51fa\u73fe\u3002\u9019\u610f\u5473\u8457\u65b0\u52a0\u5761\u4eba\u53e3\u5c0dDENV3\u7684\u514d\u75ab\u529b\u8f03\u4f4e\uff0c\u56e0\u6b64\uff0c\u5f88\u5927\u4e00\u90e8\u5206\u4eba\u53e3\u6613\u53d7DENV3\u611f\u67d3\u3002<\/p>\n

\u5230\u76ee\u524d\u70ba\u6b62\uff0c\u9084\u6c92\u6709\u91dd\u5c0dDENV\u7684\u9ad8\u5ea6\u4fdd\u8b77\u6027\u75ab\u82d7\u6216\u6cbb\u7642\u5291\u3002\u9019\u662f\u7531\u65bc\u7576\u500b\u9ad4\u5728\u7e7c\u767c\u611f\u67d3\u4e2d\u611f\u67d3\u4e86\u53e6\u4e00\u79cd\u8840\u6e05\u578b\u6642\uff0c\u91dd\u5c0d\u56db\u7a2e\u5df2\u77e5\u8840\u6e05\u578b\uff08DENV1-4\uff09\u4e2d\u7684\u4efb\u4f55\u4e00\u7a2e\u7522\u751f\u7684\u6297\u9ad4\u53ef\u80fd\u6703\u589e\u5f37\u75be\u75c5\u7684\u56b4\u91cd\u6027\u3002\u9019\u8868\u660e\u6709\u6548\u7684\u75ab\u82d7\u5fc5\u9808\u80fd\u5920\u540c\u6642\u6fc0\u767c\u91dd\u5c0d\u6240\u6709\u56db\u79cd\u8840\u6e05\u578b\u7684\u540c\u6a23\u5f37\u7684\u4fdd\u8b77\u6027\u53cd\u61c9\u3002\u6bcf\u79cd\u8840\u6e05\u578b\u4e2d\u90fd\u6709\u4e0d\u540c\u7684\u75c5\u6bd2\u682a\uff0c\u4e26\u4e14\u4f7f\u4e0d\u540c\u7684\u682a\u8868\u73fe\u51fa\u622a\u7136\u4e0d\u540c\u7684\u5f62\u72c0\uff0c\u5f9e\u800c\u4f7f\u5b83\u5011\u80fd\u5920\u9003\u907f\u5bbf\u4e3b\u514d\u75ab\u7cfb\u7d71\u7684\u6aa2\u6e2c\uff0c\u9019\u4f7f\u75ab\u82d7\u958b\u767c\u66f4\u52a0\u8907\u96dc\u3002 Duke-NUS\u5718\u968a\u5148\u524d\u767c\u73feDENV2\u7684\u8868\u9762\u53ef\u4ee5\u6839\u64da\u5bbf\u4e3b\u689d\u4ef6\u5f9e\u5149\u6ed1\u8b8a\u70ba\u985b\u7c38\u3002<\/p>\n

\u201c\u4ee5\u524d\u7684\u7d50\u69cb\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728DENV2\uff0c\u56e0\u6b64\u5176\u4ed6\u540c\u6a23\u91cd\u8981\u7684\u8840\u6e05\u578b\u6c92\u6709\u5f97\u5230\u5f88\u597d\u7684\u7814\u7a76\uff0c\u201d\u7f8e\u570b\u675c\u514b\u5927\u5b78-\u570b\u7acb\u5927\u5b78\u65b0\u50b3\u67d3\u75c5\uff08EID\uff09\u8a08\u5283\u7684Sheemei Lok\u6559\u6388\u8aaa\u3002 \u201c\u5728\u9019\u9805\u7814\u7a76\u4e2d\uff0c\u6211\u5011\u767c\u73feDENV3\u53ef\u4ee5\u5c07\u81ea\u8eab\u5f9e\u5149\u6ed1\u7684\u5713\u5f62\u9846\u7c92\u6025\u5287\u8f49\u8b8a\u70ba\u7403\u687f\u72c0\u7684\u9846\u7c92\uff08\u5982\u9ad8\u723e\u592b\u7403\u687f\uff09\uff0c\u9019\u5c07\u6709\u52a9\u65bc\u75c5\u6bd2\u9003\u907f\u5bbf\u4e3b\u7684\u514d\u75ab\u53cd\u61c9\uff0c\u75ab\u82d7\u548c\u6cbb\u7642\u65b9\u6cd5\u3002\u201d<\/p>\n

\u7814\u7a76\u5c0f\u7d44\u9084\u767c\u73fe\u4e86\u4e00\u4e9b\u80fd\u5920\u5728DENV1\uff0cDENV2\u548czika\u4e2d\u8f49\u5316\u70ba\u68cd\u72c0\u9846\u7c92\u7684\u83cc\u682a\uff0c\u5118\u7ba1\u9019\u4e9b\u83cc\u682a\u50c5\u4f54\u75c5\u6bd2\u7a2e\u7fa4\u7684\u4e00\u5c0f\u90e8\u5206\u3002\u5118\u7ba1\u5982\u6b64\uff0c\u9019\u8868\u660e\u9ec3\u75c5\u6bd2\u5177\u6709\u5c07\u81ea\u8eab\u8f49\u8b8a\u70ba\u8207\u5176\u539f\u59cb\u7d50\u69cb\u622a\u7136\u4e0d\u540c\u7684\u69cb\u8c61\u7684\u6f5b\u529b\uff0c\u9019\u6703\u4f7f\u75ab\u82d7\u548c\u6cbb\u7642\u5291\u5c0d\u5b83\u5011\u7121\u6548\u3002<\/p>\n

\u201c\u96d6\u7136\u65b0\u52a0\u5761\u6700\u8fd1\u7206\u767c\u7684\u767b\u9769\u71b1\u75c5\u4f8b\u6fc0\u589e\uff0c\u4f46\u6bcf\u5e74\u8a72\u75c5\u6bd2\u611f\u67d3\u5168\u7403\u7d044\u5104\u4eba\uff0c\u5728\u71b1\u5e36\u548c\u4e9e\u71b1\u5e36\u5730\u5340\u611f\u5730\u4e0b539\u516c\u5f0f<\/a>\u67d3\u7387\u5f88\u9ad8\u3002\u7b26\u5408\u675c\u514b\u5927\u5b78-\u7f8e\u570b\u570b\u7acb\u5927\u5b78\u8f49\u8b8a\u91ab\u5b78\u7684\u9858\u666f\uff0c\u9019\u9805\u7814\u7a76\u70ba\u7814\u7a76\u63d0\u4f9b\u4e86\u65b0\u7684\u65b9\u5411\u300294\u5927\u767c\u7db2<\/a>o\u958b\u767c\u66f4\u597d\u7684\u7642\u6cd5\u548c\u75ab\u82d7\u4f86\u6cbb\u7642\u6216\u9810\u9632\u767b\u9769\u71b1\u611f\u67d3\uff0c\u4e26\u6709\u52a9\u65bc\u5be6\u73fe\u516c\u5171\u885b\u751f\u6210\u679c\u3002\u201d\u53f0\u7063\u5a1b\u6a02\u57ce<\/a>d\u570b\u7acb\u675c\u514b\u5927\u5b78\u7814\u7a76\u9ad8\u7d1a\u526f\u9662\u9577Patrick Casey\u6559\u6388\u3002<\/p>\n

\u5718\u968a\u76ee\u524d\u6b63\u5728\u7814\u7a76\u66f4\u591aD\u767c\u767c\u7db2<\/a>ENV3\u81e8\u5e8a\u83cc\u682a\u78ba\u5b9a\u9019\u7a2e\u7d50\u69cb\u8f49\u5316\u662f\u5426\u5e38\u898b\u3002<\/p>\n

\u53c3\u8003<\/h3>\n

\u83ab\u7f85\u5167 \u7b49<\/i>\uff082020\uff09\u3002\u975e\u7403\u5f62\u5f62\u614b\u8b8a\u7570\u8b49\u660e\u4e86\u9ad8\u9ec3\u75c5\u6bd2\u7d50\u69cb\u53ef\u5851\u6027\u3002 \u81ea\u7136\u901a\u8a0a\u3002 <\/i>DOI\uff1ahttps\uff1a\/\/doi.org\/10.1038\/s41467-020-16925-y<\/p>\n

\u672c\u6587\u5df2\u5f9e\u4ee5\u4e0b\u6750\u6599\u91cd\u65b0\u767c\u5e03\u3002\u6ce8\u610f\uff1a\u6750\u6599\u7684\u9577\u5ea6\u548c\u5167\u5bb9\u53ef\u80fd\u5df2\u88ab\u7de8\u8f2f\u3002\u6709\u95dc\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u806f\u7e6b\u5f15\u7528\u7684\u5927\u6a02\u900f\u5373\u6642\u958b\u734e\u865f\u78bc<\/a>\u4f86\u6e90\u3002 <\/div>\n","protected":false},"excerpt":{"rendered":"

\u622a\u81f3\uff082020\uff09\u3002\u5e746\u670813\u65e5\u7684\u4e00\u5468\u4e2d\uff0c\u65b0\u52a0\u5761\u5171\u67091158\u4f8b\u767b\u9769\u71b1\u75c5\u4f8b\uff0c\u662f2014\u5e74\u4ee5\u4f86\u6bcf\u9031\u8a18\u9304\u7684\u6700\u9ad8\u767b\u9769\u71b1\u75c5 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"spay_email":""},"categories":[1],"tags":[707,1313,781,1337,1351,1450,1422,671,832,2241,836,1046,372,1174,695,382,560,1137,1017,1084,1146,2557,510],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":30752,"url":"https:\/\/\/%e7%96%ab%e8%8b%97%e9%a1%af%e7%a4%bapro%e5%8f%b0%e7%81%a3%e5%a8%9b%e6%a8%82%e5%9f%8e%e5%b0%8d%e5%8b%95%e7%89%a9%e7%9a%84sars-cov-2%e6%9c%89%e6%8a%97%e8%97%a5%e6%80%a7\/","url_meta":{"origin":34181,"position":0},"title":"\u75ab\u82d7\u986f\u793aPro\u53f0\u7063\u5a1b\u6a02\u57ce\u5c0d\u52d5\u7269\u7684SARS-CoV-2\u6709\u6297\u85e5\u6027","date":"23 6 \u6708, 2021","format":false,"excerpt":"\u5927\u591a\u6578\u60a3\u6709COVID-19\u7684\u4eba\u60a3\u6709\u76f8\u5c0d\u8f03\u8f15\u7684\u75be\u75c5\uff0c\u4f46\u4e00\u90e8\u5206\u4eba\u6703\u767c\u5c55\u70ba\u56b4\u91cd\u7684\u80ba\u708e\u548c\u547c\u5438\u8870\u7dda\u4e0a\u771f\u4eba\u9ebb\u5c07\u63a8\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":32993,"url":"https:\/\/\/%e8%82%9d%e7%b4%a0%e5%8f%af%e4%bb%a5%e7%94%a8%e6%96%bc%e9%98%bb%e6%ad%a2sars-cov-2-f%e7%9c%9f%e4%ba%ba%e5%a8%9b%e6%a8%82%e5%9f%8erom%e6%84%9f%e6%9f%93%e4%ba%ba%e9%a1%9e%e7%b4%b0%e8%83%9e%e5%97%8e\/","url_meta":{"origin":34181,"position":1},"title":"\u809d\u7d20\u53ef\u4ee5\u7528\u65bc\u963b\u6b62SARS-CoV-2 F\u771f\u4eba\u5a1b\u6a02\u57cerom\u611f\u67d3\u4eba\u985e\u7d30\u80de\u55ce\uff1f","date":"4 9 \u6708, 2021","format":false,"excerpt":"\u6839\u64da\u672c\u9031\u767c\u8868\u7684\u7814\u7a76\u7d50\u679c\uff0c\u4e00\u7a2e\u5df2\u88ab\u98df\u54c1\u548c\u85e5\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u7684\u666e\u901a\u85e5\u7269\u4e5f\u53ef\u80fd\u662f\u6297\u64caCOVID-19\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":31698,"url":"https:\/\/\/ms%e8%97%a5%e7%89%a9%e5%8f%af%e9%98%bb%e6%ad%a2hiv%e6%84%9f%e6%9f%93%e6%96%b0%e5%a4%a9%e4%b8%8b%e5%a8%9b%e6%a8%82%e5%9f%8e%e5%92%8c%e4%ba%ba%e9%a1%9e%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e7%9a%84\/","url_meta":{"origin":34181,"position":2},"title":"MS\u85e5\u7269\u53ef\u963b\u6b62HIV\u611f\u67d3\u65b0\u5929\u4e0b\u5a1b\u6a02\u57ce\u548c\u4eba\u985e\u514d\u75ab\u7d30\u80de\u7684\u50b3\u64ad","date":"23 7 \u6708, 2021","format":false,"excerpt":"\u82ac\u6208\u83ab\u5fb7\uff08Fingolimod\uff09\uff0c\u4e00\u7a2eFDA\u6279\u51c6\u7684\u514d\u75ab\u6291\u88fd\u5291\uff0c\u7528\u65bc\u6cbb\u7642\u591a\u6709\u7121\u504f\u8ca1\u904b\u767c\u6027\u786c\u5316\u75c7\u91d1\u5408\u767c\u5a1b\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":33731,"url":"https:\/\/\/mini-bra%e5%8d%9a%e9%a6%ac%e5%a8%9b%e6%a8%82%e5%9f%8e%e7%a0%94%e7%a9%b6%e7%9a%84%e7%99%bc%e7%8f%be%e8%a1%a8%e6%98%8esars-cov-2%e5%8f%af%e4%bb%a5%e6%84%9f%e6%9f%93%e4%ba%ba%e8%85%a6\/","url_meta":{"origin":34181,"position":3},"title":"\u201c Mini-bra\u535a\u99ac\u5a1b\u6a02\u57ce\u201d\u7814\u7a76\u7684\u767c\u73fe\u8868\u660eSARS-CoV-2\u53ef\u4ee5\u611f\u67d3\u4eba\u8166\u7d30\u80de","date":"25 9 \u6708, 2021","format":false,"excerpt":"\u4f86\u81ea\u5169\u500b\u7d04\u7ff0\u00b7\u970d\u666e\u91d1\u65af\u5927\u5b78\u6a5f\u69cb\u7684\u8de8\u5b78\u79d1\u5718\u968a\uff0c\u5305\u62ec\u5f6d\u535a\u516c\u5171\u885b\u96fb\u7af6\u904b\u5f69\u5206\u6790\u751f\u5b78\u9662\u7684\u795e\u7d93\u6bd2\u7406\u5b78\u5bb6\u548c\u75c5\u6bd2\u5b78\u5bb6\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":28016,"url":"https:\/\/\/rap%e5%8f%b0%e7%81%a3%e5%a8%9b%e6%a8%82%e5%9f%8eid%e6%b8%ac%e8%a9%a6%e5%8f%af%e4%bb%a5%e8%ad%98%e5%88%a5%e6%9c%aa%e7%9f%a5%e7%9a%84%e5%85%a8%e8%ba%ab%e6%84%9f%e6%9f%93%e5%8e%9f%e5%9b%a0\/","url_meta":{"origin":34181,"position":4},"title":"Rap\u53f0\u7063\u5a1b\u6a02\u57ceid\u6e2c\u8a66\u53ef\u4ee5\u8b58\u5225\u672a\u77e5\u7684\u5168\u8eab\u611f\u67d3\u539f\u56e0","date":"25 3 \u6708, 2021","format":false,"excerpt":"\u52a0\u5dde\u5927\u5b78\u820a\u91d1\u5c71\u5206\u6821\u7684\u79d1\u5b78\u5bb6\u958b\u767c\u4e86\u4e00\u7a2e\u80fd\u5920\u6b78\u96f6\u7684\u81e8\u5e8a\u5be6\u9a57\u5ba4\u6e2c\u8a66\u4e5d\u5dde\u5a1b\u6a02\u57ce\u5728\u77ed\u77ed\u516d\u500b\u5c0f\u6642\u5167\u5c31\u53ef\u5c0d\u906d\u53d7\u56b4\u91cd\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":32680,"url":"https:\/\/\/impro%e5%a8%9b%e6%a8%82%e5%9f%8e%e6%8e%a8%e8%96%a6ptrved%e7%97%85%e6%af%92rna%e8%a4%87%e8%a3%bd%e6%a9%9f%e7%9a%84%e5%9c%96%e5%83%8f\/","url_meta":{"origin":34181,"position":5},"title":"Impro\u5a1b\u6a02\u57ce\u63a8\u85a6ptrved\u75c5\u6bd2RNA\u8907\u88fd\u6a5f\u7684\u5716\u50cf","date":"26 8 \u6708, 2021","format":false,"excerpt":"\u5c0e\u81f4COVID-19\u7684\u51a0\u72c0\u75c5\u6bd2SARS-CoV-2\u88ab\u7a31\u70ba\u6b63\u93c8RNA\u75c5\u6bd2\uff0c\u56e0\u70ba\u5b83\u5b58\u5132\u548c\u5fa9\u5236\u5176\u907a\u50b3\u7269\u8cea\u7684\u2026","rel":"","context":"\u5728\u300c\u5a1b\u6a02\u57ce\u300d\u4e2d","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/\/wp-json\/wp\/v2\/posts\/34181"}],"collection":[{"href":"https:\/\/\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/\/wp-json\/wp\/v2\/comments?post=34181"}],"version-history":[{"count":0,"href":"https:\/\/\/wp-json\/wp\/v2\/posts\/34181\/revisions"}],"wp:attachment":[{"href":"https:\/\/\/wp-json\/wp\/v2\/media?parent=34181"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/\/wp-json\/wp\/v2\/categories?post=34181"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/\/wp-json\/wp\/v2\/tags?post=34181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}